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you are allergic to any ingredient in Doxycycline, or to similar medicines such as demeclocycline (Declomycin), minocycline (Dynacin, Minocin, Solodyn, Vectrin), or tetracycline (Brodspec, Panmycin, Sumycin, Tetracap)
you are taking acitretin, isotretinoin, or a penicillin (eg, amoxicillin)
you have recently received or will be receiving a live oral typhoid vaccine.

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if you are pregnant, planning to become pregnant, or are breast-feeding
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if you have liver or kidney disease, you may need a dose adjustment or special tests to safely take Doxycycline.

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Important safety information:

Be sure to use Doxycycline for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
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Doxycycline may interfere with certain lab tests. Be sure your doctor and lab personnel know you are using Doxycycline.
Pregnancy and breast-feeding: Doxycycline has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Doxycycline while you are pregnant. Doxycycline is found in breast milk. Do not breastfeed while taking Doxycycline.

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Loss of appetite; nausea; sensitivity to sunlight; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody stools; chest pain; dark urine; decreased urination; fever, chills, or sore throat; moderate to severe sunburn; severe diarrhea; severe or persistent headache; stomach pain or cramps; throat irritation; trouble swallowing; unusual bruising or bleeding; unusual joint pain; unusual tiredness; vaginal irritation or discharge; vision changes; yellowing of the skin or eyes.

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